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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLRE1A
All Species:
8.48
Human Site:
S590
Identified Species:
16.97
UniProt:
Q6PJP8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6PJP8
NP_055696.3
1040
116422
S590
I
N
L
N
P
V
P
S
P
N
Q
K
R
S
S
Chimpanzee
Pan troglodytes
XP_508045
1040
116405
S590
I
N
L
N
P
V
P
S
P
N
Q
K
R
S
S
Rhesus Macaque
Macaca mulatta
XP_001090942
1039
116662
P589
G
I
N
L
N
P
V
P
S
P
N
K
K
R
S
Dog
Lupus familis
XP_535018
1074
119811
V624
G
M
N
L
N
P
V
V
S
P
N
E
K
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIC3
1026
113549
V576
E
G
P
N
V
S
P
V
V
S
P
N
Q
K
R
Rat
Rattus norvegicus
NP_001099671
1026
112807
S576
P
K
A
S
P
V
V
S
P
S
E
K
R
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513453
994
111830
R561
S
P
K
E
Q
H
S
R
K
R
K
R
K
A
D
Chicken
Gallus gallus
Q5QJC4
972
108310
F539
K
Q
M
D
I
G
V
F
F
G
L
K
P
K
V
Frog
Xenopus laevis
NP_001093331
932
103215
I500
K
G
M
K
Q
M
D
I
G
V
F
F
G
L
K
Zebra Danio
Brachydanio rerio
XP_002664006
926
102909
S494
R
E
A
D
L
Q
K
S
R
R
V
R
V
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321063
382
43088
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38961
484
55143
K52
G
F
A
S
D
F
Y
K
A
G
S
D
W
S
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
93.5
71.6
N.A.
62.8
61.8
N.A.
49.7
43.4
40.2
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
96
78.9
N.A.
72.5
72.5
N.A.
63.3
58.2
55.4
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
13.3
40
N.A.
0
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
26.6
60
N.A.
26.6
20
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.6
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
27.1
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
0
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
17
9
0
9
0
0
0
0
9
0
0
9
% D
% Glu:
9
9
0
9
0
0
0
0
0
0
9
9
0
0
9
% E
% Phe:
0
9
0
0
0
9
0
9
9
0
9
9
0
0
0
% F
% Gly:
25
17
0
0
0
9
0
0
9
17
0
0
9
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
17
9
9
9
0
0
9
9
9
0
9
42
25
17
9
% K
% Leu:
0
0
17
17
9
0
0
0
0
0
9
0
0
9
0
% L
% Met:
0
9
17
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
17
25
17
0
0
0
0
17
17
9
0
0
0
% N
% Pro:
9
9
9
0
25
17
25
9
25
17
9
0
9
9
0
% P
% Gln:
0
9
0
0
17
9
0
0
0
0
17
0
9
0
0
% Q
% Arg:
9
0
0
0
0
0
0
9
9
17
0
17
25
17
17
% R
% Ser:
9
0
0
17
0
9
9
34
17
17
9
0
0
34
34
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
25
34
17
9
9
9
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _